The mechanisms of action for Glucosamine include maintaining elasticity, strength and resilience of the cartilage, the inhibition of proteolytic enzymes (elastase, hyaluronidase) and promotion of glycosaminoglycan and proteoglycan synthesis. Glucosamine, which is produced naturally in the body, plays a key role in building cartilage; the tough connective tissue that cushions the joints. Several scientific studies suggest that glucosamine may be an effective treatment for osteoarthritis (OA).