Metoclopramide & Paracetamol is used in the treatment of migraine. It prevents pain signals and fever associated with migraine. It also blocks certain substances in the brain that trigger nausea or vomiting during migraine headaches. Metoclopramide & Paracetamol is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.