Naproxen & Domperidone are used together to relieve the symptoms of migraines, such as headaches, nausea, and vomiting. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, while Domperidone helps prevent nausea and vomiting by improving gastric motility. This combination provides comprehensive relief from migraine discomfort. Naproxen is a non-selective, non-steroidal anti-inflammatory drug. The mechanism behind its effectiveness involves inhibiting the production of prostaglandins, which are substances in the body that cause pain and inflammation. By blocking these chemicals, Naproxen helps alleviate various conditions associated with pain and inflammation. Domperidone is an anti-emetic drug that also delays gastrointestinal emptying. It works as a prokinetic by blocking dopamine receptors, which helps prevent nausea and vomiting.