Hydrochlorothiazide+Olmesartan Medoxomil belongs to a group of medications called 'anti-hypertensives' primarily used to treat high blood pressure (hypertension). High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications. Olmesartan Medoxomil+Hydrochlorothiazide is a combination of two medicines: Olmesartan medoximil and Hydrochlorothiazide. Olmesartan medoximil is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Olmesartan Medoxomil+Hydrochlorothiazide lowers blood pressure and fluid overload.