Additional information
Therapeutic Segment | Tuberculosis |
---|---|
Dosage Form | Tablets |
Specialities | Chest Physician |
As directed by physician
However, the mechanism of action of pyrazinamide is poorly understood because of its unusual properties. Here we show that pyrazinoic acid, the active moiety of pyrazinamide, disrupted membrane energetics and inhibited membrane transport function in Mycobacterium tuberculosis.