Additional information
| Dosage Form | Tablets |
|---|---|
| Specialities | Neurologist, Physician, Psychiatrist |
| Packing | 1 x 10 (Blister) |
| Therapeutic Segment | Antidepressants |
Vortioxetine 10 mg Tablets are an antidepressant medication used in the treatment of major depressive disorder (MDD) in adults. It helps improve mood, concentration, and overall cognitive function, supporting better emotional balance and quality of life.
- Reduces symptoms of depression such as sadness, loss of interest, and fatigue
- Improves cognitive function and concentration affected by depression
- Helps restore emotional stability and overall well-being
- Can be used alone or as adjunctive therapy in depression
- Generally associated with a low risk of weight gain and sexual dysfunction compared to some other antidepressants
Take this medicine in the dose and duration as advised by your doctor. Swallow the tablet whole with water, preferably at the same time each day. Regular follow-up is recommended to monitor therapeutic response and side effects.
Vortioxetine is a novel multimodal antidepressant that acts as a serotonin (5-HT)3, 5-HT7, and 5-HT1D receptor antagonist; 5-HT1B receptor partial agonist; 5-HT1A receptor agonist; and 5-HT transporter inhibitor in vitro. In preclinical and clinical studies vortioxetine demonstrates positive effects on cognitive dysfunction. Vortioxetine's effect on cognitive function likely involves the modulation of several neurotransmitter systems.
Acute and chronic administration of vortioxetine resulted in changes in histamine concentrations in microdialysates collected from the rat prefrontal cortex and ventral hippocampus. Based on these results and a literature review of the current understanding of the interaction between the histaminergic and serotonergic systems and the role of histamine on cognitive function, we hypothesize that vortioxetine through an activation of the orexinergic system stimulates the tuberomammilary nucleus and enhances histaminergic neurotransmission, which contributes to vortioxetine's positive effects on cognitive function.
As directed by physician
